Reducing Neonatal Sepsis With Probiotics.

Grant number: 454629 | Funding period: 2007 - 2010

Completed

Abstract

Currently, premature infants are born without the normal immune defenses of infants born at the correct time because the protective factors that normally pass from the mother to the baby during the last few months of pregnancy have not had time to do so. In addition the tiny premature infants are at risk because they need the expertise of intensive care and are therefore separated from their parents and their parents' organisms which healthy term infants normally pick up from the birth canal and their parents skin. The infants commonly develop infections from organisms living on their skin surfaces or inside their lungs, stomach or bowels. The babies are living in a hospital environment whic..

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Related publications (7)

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The effect of probiotic supplementation on the gut microbiota of preterm infants

EL Plummer, JA Danielewski, SM Garland, J Su, SE Jacobs, GL Murray

2021-01-01

Introduction. Probiotic supplementation of preterm infants may prevent serious morbidities associated with prematurity. Aim. To in..

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Postnatal probiotics and allergic disease in very preterm infants: Sub-study to the ProPrems randomized trial

EL Plummer, A Chebar Lozinsky, JM Tobin, JB Uebergang, C Axelrad, SM Garland, SE Jacobs, MLK Tang

2020-01-01

Background: Probiotic supplementation to mothers and/or their term-born infants has been suggested to prevent allergic disease, in..

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Gut microbiota of preterm infants supplemented with probiotics: Sub-study of the ProPrems trial

EL Plummer, DM Bulach, GL Murray, SE Jacobs, SN Tabrizi, SM Garland

2018-11-13

Background: The ProPrems trial, a multi-center, double-blind, placebo-controlled randomized trial, previously reported a 54% reduc..

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Probiotics, prematurity and neurodevelopment: Follow-up of a randomised trial

SE Jacobs, L Hickey, S Donath, GF Opie, PJ Anderson, SM Garland, JLY Cheong, L Gold, KL Sia, JM Tobin, SN Tabrizi, M Pirotta, MLK Tang, CJ Morley, K Tan, A Lewis, A Veldman, E Carse, J Travadi, IMR Wright

2017-12-01

Objective To determine the impact of one probiotics combination on the neurodevelopment of very preterm children at 2–5 years corr..

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Cross-colonization of infants with probiotic organisms in a neonatal unit

L Hickey, SM Garland, SE Jacobs, CPF O'Donnell, SN Tabrizi

2014-12-01

This study aimed to assess probiotic cross-colonization between infants in a neonatal unit where probiotics were being administere..

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Probiotics in neonatology

L Hickey, SE Jacobs, SM Garland

2012-09-01

Probiotics are micro-organisms that confer health benefits on the host. Postulated mechanisms include: increasing resistance of th..

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The ProPrems trial: Investigating the effects of probiotics on late onset sepsis in very preterm infants

SM Garland, JM Tobin, M Pirotta, SN Tabrizi, G Opie, S Donath, MLK Tang, CJ Morley, L Hickey, L Ung, SE Jacobs

2011-08-04

Background: Late onset sepsis is a frequent complication of prematurity associated with increased mortality and morbidity. The com..

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